Kathy, Your post makes me sad.  I also suspected the Metacam to be a 
cause in my Daisy's kidney failure. I started giving her the Metacam 
for arthritis and it really seemed to help.  Her appetite did go down 
and when I couldn't get her to eat enough after trying everything, I 
finally stopped giving her the med.  I lost her to renal failure a 
couple of months later. When I asked the vet if he thought the 
Metacam might have had something to do with it, he said no. I found 
it kind of suspicious since she had had fine kidney numbers when I 
started the pain med.

Kerry